{"id":521,"date":"2023-06-12T13:18:08","date_gmt":"2023-06-12T11:18:08","guid":{"rendered":"https:\/\/elypsun.fr\/?p=521"},"modified":"2023-09-03T23:15:04","modified_gmt":"2023-09-03T21:15:04","slug":"chez-la-femme-lhorloge-circadienne-plus-active-que-chez-lhomme","status":"publish","type":"post","link":"https:\/\/elypsun.fr\/en\/chez-la-femme-lhorloge-circadienne-plus-active-que-chez-lhomme\/","title":{"rendered":"In women, the circadian clock is more active than in men."},"content":{"rendered":"

[et_pb_section fb_built=\u00a0\u00bb1″ _builder_version=\u00a0\u00bb4.18.0″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb locked=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb theme_builder_area=\u00a0\u00bbpost_content\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.21.0″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb hover_enabled=\u00a0\u00bb0″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb column_structure=\u00a0\u00bb3_5,2_5″ theme_builder_area=\u00a0\u00bbpost_content\u00a0\u00bb sticky_enabled=\u00a0\u00bb0″][et_pb_column type=\u00a0\u00bb3_5″ _builder_version=\u00a0\u00bb4.18.0″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb theme_builder_area=\u00a0\u00bbpost_content\u00a0\u00bb][et_pb_text module_class=\u00a0\u00bblien_blog\u00a0\u00bb _builder_version=\u00a0\u00bb4.21.0″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb hover_enabled=\u00a0\u00bb0″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb theme_builder_area=\u00a0\u00bbpost_content\u00a0\u00bb sticky_enabled=\u00a0\u00bb0″]<\/p>\n

Durant la journ\u00e9e, l\u2019activit\u00e9 de nos g\u00e8nes oscille en deux grandes vagues, l\u2019une matinale, l\u2019autre vesp\u00e9rale. Mais ces vagues, plus amples chez la femme que chez l\u2019homme, s\u2019amenuisent avec l\u2019\u00e2ge, montre une \u00e9tude dans la revue \u00ab Science \u00bb.<\/p>\n

C\u2019est une histoire de g\u00e8nes dont l\u2019activit\u00e9 oscille, dans nos cellules, au cours du jour et de la nuit. Formant deux grandes vagues, l\u2019une le matin, l\u2019autre le soir, dont la hauteur varie selon nos tissus. Le groupe de g\u00e8nes concern\u00e9s diff\u00e8re selon nos tissus. Par ailleurs, ces vagues apparaissent plus marqu\u00e9es chez les femmes que chez les hommes, mais elles sont \u00e9mouss\u00e9es par l\u2019\u00e2ge dans les deux sexes.<\/span><\/span><\/p>\n

Telles sont, en substance, les d\u00e9couvertes d\u2019une exploration in\u00e9dite, men\u00e9e sur des tissus humains pr\u00e9lev\u00e9s chez 914 donneurs peu apr\u00e8s leur d\u00e9c\u00e8s. Publi\u00e9e dans la revue Science<\/em> du 3 f\u00e9vrier, cette analyse met ainsi au jour la m\u00e9canique intime de notre horloge circadienne<\/a>, cet engrenage mol\u00e9culaire qui donne \u00e0 nos cellules l\u2019heure de la journ\u00e9e \u2013 elles pourront ainsi ajuster leurs t\u00e2ches aux besoins de l\u2019organisme.<\/span><\/span><\/p>\n

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\u00a0<\/span><\/span><\/div>\n
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Mais pourquoi ce nom d\u2019horloge \u00ab circadienne \u00bb \u2013 du latin circa<\/em>,\u00ab proche de \u00bb, et dies<\/em>, \u00ab jour \u00bb ? Parce que cette pendule, chez notre esp\u00e8ce, est r\u00e9gl\u00e9e sur une p\u00e9riode moyenne de vingt-quatre heures et douze minutes. Cette dur\u00e9e d\u00e9pend toutefois des individus. Chez les couche-t\u00f4t, l\u2019horloge est plus rapide (sa p\u00e9riode tend vers vingt-trois heures et trente minutes) ; chez les couche-tard, elle est plus lente (vingt-quatre heures et trente minutes). Quel que soit notre chronotype, notre horloge interne doit se caler sur un rythme de vingt-quatre heures. Elle utilise pour cela des synchronisateurs externes : lumi\u00e8re du jour, rythme de nos repas et de nos activit\u00e9s quotidiennes\u2026<\/span><\/span><\/p>\n

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Lemonde: lire l’article entier en cliquant ici<\/u><\/a><\/p>\n

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Chez les femmes, l’horloge circadienne est plus active que chez les hommes, avec des oscillations g\u00e9n\u00e9tiques plus prononc\u00e9es. Cependant, ces oscillations diminuent avec l’\u00e2ge. Une \u00e9tude r\u00e9v\u00e8le cette m\u00e9canique intime \u00e0 partir d’\u00e9chantillons de tissus humains. Notre horloge circadienne est r\u00e9gl\u00e9e sur une p\u00e9riode moyenne de 24 heures et 12 minutes, ajust\u00e9e par des synchroniseurs externes tels que la lumi\u00e8re du jour et les activit\u00e9s quotidiennes.<\/p>","protected":false},"author":1,"featured_media":109,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-521","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-et-actualite"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/posts\/521","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/comments?post=521"}],"version-history":[{"count":4,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/posts\/521\/revisions"}],"predecessor-version":[{"id":970,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/posts\/521\/revisions\/970"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/media\/109"}],"wp:attachment":[{"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/media?parent=521"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/categories?post=521"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/elypsun.fr\/en\/wp-json\/wp\/v2\/tags?post=521"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}